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influenza virus and the host cell surface sialic acid receptor binding to mediate virus entry into the cell to complete replication. Such receptors in the human respiratory tract and the different types of birds respiratory tract,barbour pas cher, such as the respiratory tract in poultry with  -2,barbour lyon,3 sialic acid receptor type based,doudounes moncler vente, so this receptor is also often referred to as avian-type sialic acid receptor; in person airway surface,nike sito ufficiale, mainly the distribution of  -2,air jordan shop,6 sialic acid receptor type,chaussure louboutin pas cher, known as man-sialic acid receptors. Influenza virus surface called hemagglutinin (HA) protein of influenza virus tends to determine the type of binding which sialic acid receptor. Scientists after comparing different subtypes of influenza virus HA sequences found.
so it is possible restructuring process making the original virus only infected birds to humans,air jordan donna. (Freelance writer _ Yu Tao / virology researcher) Q: H7N9 virus from person to person spread it? # Person to person # A: No evidence of human to human transmission,nike air max.
HA protein of some kinds of amino acids at key sites determines its specificity for sialic acid receptor binding. In general,basket louboutin, the human influenza virus priority to recognize human type sialic acid receptor, and the avian flu virus is a priority to identify avian-type sialic acid receptors. Under normal circumstances,barbour soldes, the bird flu virus does not come into contact with the human body. However, in some cases, such as human and avian relatively long-term close contact, such that the avian influenza virus has the opportunity to come into contact with people, and it is possible to repeatedly spread between birds and people with each other. In this case, the bird flu virus may be some mutations cause HA key sites kinds of amino acids to change, so that the bird flu virus HA protein can bind to human sialic acid receptor type, so the bird flu virus is likely to infect humans airway epithelial cells. This process makes the avian influenza virus to adapt to the new host to obtain a mutation,air max sito ufficiale, of course, these mutations may not only include the changes in the HA protein amino acid. In addition,scarpe nike online, the presence of porcine respiratory and poultry while man-type sialic acid receptor, so human-type flu virus and avian influenza virus can infect pigs and are likely to occur in pigs in vivo recombination.
Any kind of virus infection has a host-specific, depending on many factors, one of which the most important is whether the combination of the virus-specific host cell membrane surface receptors. Influenza virus infection is generally considered to host specificity,chaussure louboutin pas cher, no cross-species transmission. Influenza viruses can infect humans typically human influenza virus (such as H1, H2 and H3 type) or a human-type and recombinant avian influenza virus type (such as H5 and H7 type,barbour homme, etc.). In August 1997,doudoune homme moncler vente, scientists in China,nike air jordan, Hong Kong A 3-year-old child flu deaths in vivo isolated the H5N1 highly pathogenic avian influenza virus,air jordan shop, which was first discovered H5 avian influenza virus infection of human cases in the world,doudoune homme moncler, a total of 18 people infected in which six people died. It makes people realize that the avian influenza virus infection is directly across the species exist. Influenza viruses usually infect humans or animals airway epithelial cells.
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